Drugs acting on blood part-2 | KDT Pharmacology mcq

Which of the following is/are dietary source of vitamin K 

(A) Green Leafy Vegitable

(B) Liver

(C) Chees

(D) All of the above

Ans : (B) Liver


Total estimated requirement of vitamin K for an adult is around 

(A) 50 to 100 μg/day

(B) 100 to 200 μg/day

(C) 200 to 300 μg/day

(D) 300 to 350 μg/day

Ans : (A) 50 to 100 μg/day

Find the correct statement regarding Fat vitamin K 

(A) Absorbed from intestine

(B) Absorbed via lymph

(C) Required bile salt for absorption

(D) All are correct

Ans : (D) All are correct

Which of the following may be the cause of vitamin K deficiency (Tick) 

(A) Liver Disease

(B) Obstructive Jaundice

(C) Malabsorption

(D) Long term antimicrobial therapy

Local Haemostasis are also known as 

(A) Stabilizers

(B) Styptics

(C) Coagulant

(D) Both A and C

Ans : (B) Styptics

Heparin is an example of

(A) Coagulants

(B) Anticoagulants

(C) Styptics

(D) All of the above

Ans : (B) Anticoagulants

Heparin were discovered in 

(A) 1919

(B) 1918

(D) 1917

(E) 1916

Ans : (E) 1916

Heparin were obtained from 

(A) Lungs

(B) Liver

(C) Kidney

(D) Brain tissue

Ans : (B) Liver

Who have given "Heparin" as its name 

(A) Howell and Holt in 1918

(B) Howell and Holt in 1916

(C) Howell and Holt 1917

(D) Howell and Holt in 1919

Ans : (A) Howell and Holt in 1918

Molecular weight of heparin is around

(A) 100 to 2000

(B) 5000 to 10000

(C) 10000 to 20000

(D) 20000 to 50000

Ans : (C) 10000 to 20000

Which of the following is not an example of parenteral anticoagulants 

(A) Heparin

(B) Fondaparinux

(C) Danaparoid

(D) Dabigatran

Ans : (D) Dabigatran

Find the example of vitamin K antagonist 

(A) Heparin

(B) Bivalirudin

(C) Argatroban

(D) Warfarin Sod.

Ans : (D) Warfarin Sod.

Find the correct statement regarding pharmacokinetics of heparin 

(A) Heparin is large highly ionized molecule

(B) Injected IV = Acts Instantaneously

(C) Injected SC = Take around 60 minutes

(D) All are correct

Ans : (D) All are correct

Heparin released from mast cells is degraded by tissue macrophage and it is not a physiologically circulating anticoagulants 

(A) True

(B) False

Ans : (A) True

Heparin should not be mixed with which of the following agent in same syringe or infusion bottles 

(A) Penicillin

(B) Tetracycline

(C) Hydrocortisone

(D) All of the above

Ans : (D) All of the above

heparin is generally not given via IM route because 

(A) Its extremely painfull

(B) This cause hematomas

(C) This route will not deliver drug properly

(D) All of the above

Ans : (B) This cause hematomas

Find the ADE associated with heparin use

(A) Bleeding

(B) Heparin induced thrombocytopenia

(C) Transient and reversible alopecia

(D) All of the above

Ans : (D) All of the above

Heparin is contraindicated in 

(A) Bleeding disorder

(B) Severe hypertension (Risk of cerebral hemorrhage)

(C) Subacute bacterial endocarditis

(D) All of the above

Ans : (D) All of the above

Molecular weight of Low MW heparin is around

(A) 3000 to 7000

(B) 7000 to 9000

(C) 1000

(D) 5000

Ans : (A) 3000 to 7000

Which of the following is advantage of low molecular weight heparin over high molecular weight heparin 

(A) Better subcutaneous bioavailability

(B) Longer and more consistent monoexponentially biological half life

(C) Laboratory monitoring is not needed

(D) All of the above

Ans : (D) All of the above

Which of the following is heparin antagonist 

(A) Protamine sulfate

(B) Propionate hydrochloride

(C) Parabionin

(D) Both A and C

Ans : (A) Protamine sulfate

Protamine sulfate is obtained from (MOST Important) 

(A) Liver of certain fish

(B) Lungs of certain fish

(C) Sperm of certain fish

(D) Urine of certain fish

Ans : (C) Sperm of certain fish

Protamine should be injected 

(A) Slowly

(B) Rapidly

(C) Speed is not a matter

(D) Speedily and then slowly

Ans : (A) Slowly

Rate of protamine injection is (For IV)

(A) 05 mg/min

(B) 20 mg/min

(C) 30 mg/min

(D) 01 mg/min

Ans : (A) 05 mg/min

Warfarin were initially used as (Before its anticoagulant activity) 

(A) Rat poison

(B) Hair Remover

(C) Hair Tonic

(D) Meiotic agents

Ans : (A) Rat poison

Warfarin is active in 

(A) In vivo

(B) In vitro

(C) Both In vivo and in vitro

(Dl Question is not appropriate

Ans : (A) In vivo

Select factors which may decrease the effect of coumarin 

(A) Pregnancy

(B) Nephrotic syndrome

(C) Genetic warfarin resistance

(D) All of the above

Ans : (D) All of the above

Source of warfarin is 

(A) Hog Lungs

(B) Pig Intestine

(C) Pig Brain

(D) Synthetic

Ans : (D) Synthetic

What will be the route of administration for warfarin 

(A) Intravenous

(B) Sub Cutaneous

(C) Oral

(D) Oral and Parenteral Both

Ans : (C) Oral

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